Agent 47 (Timothy Olyphant) is a professional assassin for hire. 47 are the last two digits of the barcode tattooed on the nape of his neck, and his only name. The hunter becomes the hunted when 47 gets caught up in a political takeover. Both Interpol and the Russian military chase the Hitman across Eastern Europe as he tries to find out who set him up and why they're trying to take him out of the game.