Leonard Zelig is a social quick-change artist whose neurotic insecurity forces him to mimic - mentally and physically - whomever he's with. Treated by Dr. Eudora Fletcher, Zelig is slowly cured, and in the process goes from side-show freak to national celebrity - to Eudora's fiance! But when misdeeds from Zelig's multiple personality past star to surface (larceny, bigamy and an unauthorized appendectomy), the human chameleon is on the run again, and Eudora must search the world over to find - and save - the only man who's every man she's ever wanted!