John Steinbeck’s classic comes magnificently to life in this beautiful and stirring film starring Oscar® nominees* John Malkovich and Gary Sinise. Directed by Sinise from an adaptation by Oscar® winner* Horton Foote, this flawless miracle of movie-making” (Susan Granger, “American Movie Classics”) is a must-see for all audiences. Best friends Lennie (Malkovich) and George (Sinise) find themselves unemployed in Depression-era California, unable to keep jobs because of Lennie’s childlike mentality. But once they get hired at the Tyler Ranch, they enjoy a brief period of stability– until their supervisor's wife (Sherilyn Fenn) becomes the victim of Lennie’s compassion, forcing George to make a compassionate decision of his own.