Set on the moon in the year 2087, where audacious nightclub owner Pluto Nash (Eddie Murphy) finds himself in hot water when he refuses to sell his club to the local mob. The lunar gangsters are helping the mysterious Rex Crater mastermind a plan to take over the moon. Joining Pluto in the danger and lunacy are Dina Lake (Rosario Dawson), a beautiful earthling who has traveled to the moon to further her singing ambitions, and Pluto's bodyguard Bruno (Quaid) - a robot quickly approaching obsolescence.