The FBI agent Sean Archer's (John Travolta) ordeal is only beginning after finally capturing his nemesis, Castor Troy (Nicolas Cage), an elusive terrorist who claimed the life of Archer's son. While Troy languishes in a coma, Archer surgically "borrows" Troy's face in an attempt to gather evidence about Troy's last bomb -- which is currently ticking away in a Los Angeles office building. Trouble ensues when Troy wakes up faceless and borrows Archer's face. Now both men struggle to blow each other away while adapting to their new identities.