Two fathers (Eddie Murphy, Jeff Garlin) lose their jobs in product development at a large food company and are forced to take their sons out of the exclusive Chapman Academy and become stay-at-home fathers. With no job possibilities on the horizon, the two dads open their own day care facility, "Daddy Day Care," and employ some fairly unconventional and sidesplitting methods of caring for children. As "Daddy Day Care" starts to catch on, it launches them into a highly comedic rivalry with Chapman Academy's tough-as-nails director (Anjelica Huston) ...who has driven all previous competitors out of business.